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Bonehead was a bullying Earth punk who embarrassed Melvin in front of girls. He later attempts to fight Toxie (who was actually Melvin after an accident bestowed him with superhuman abilities) when he finds Bonehead and his friends harassing Yvonne. In self-defense, Toxie throws him into a barrel of acid rain in the first episode resulting in his skeletal appearance. Bonehead then joins forces with Dr. Killemoff. He was mostly brainless and incompetent. He is based on Bozo from the first Toxic Avenger movie (this is due to the fact the cartoon is very loosely a spin-off of this franchise, toned down for children).

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