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Bloody Mary is a vampire and the main antagonist of inFamous 2 DLC, Festival of Blood.
When Mary was once a human, she becomes ill and is about to die. Just then, a vampire named Marco finds her too much beautiful to die that he turned her into a vampire. Since then, the two go on a rampaging spree of killing and converting people into vampires.
Father Ignatius, the priest who is in Mary's deathbed, kills Marco, believing that she would turn human again. However, it didn't work and Mary swears revenge on him. She is killed by being burned to death by a pyre.
Years later, she is resurrected when her followers captured Cole McGrath and uses his blood for her corpse. Once that's done, Mary turns Cole into a vampire. She is killed again when the catacombs explode with her.